Hepatitis B is most prevalent in the western Pacific region and in Africa, where at least 6% of the adult population is infected. An estimated 257 million people are living with hepatitis B worldwide. In the United States, a total of 3,322 cases of acute hepatitis B were reported to CDC in 2018, but actual estimates were closer to 21,600. About 862,000 are estimated to be living with chronic, long-term hepatitis B in the United States.
In 2018, there were 3,621 new cases of hepatitis C reported to CDC. However, actual estimates are closer to 50,300 new cases during 2018. In 2016, an estimated 2.4 million people were living with chronic hepatitis C in the United States.